Chemical biocides are regulated by EPA under Federal pesticide law. A product must be registered by EPA for a specific use before it can be legally used for that purpose. The specific use(s) must appear on the pesticide (e.g., biocide) label, along with other important information. It is a violation of federal law to use a pesticide product in any manner inconsistent with the label directions.
Simon explained the entire process in detail and took the time to show me what they were doing, how they were doing it, and the effects.  In his initial examination of my air duct system, he discovered dust/residue from when the house was built, such as drywall dust.  This was in my air system, and I was shocked.  Not only did they thoroughly clean out all traces of this built up layer of contaminants, but showed me "before and after".  In addition to completely cleaning the air duct system throughout the house (believe me - the inside of the air ducts looked brand new), they sanitized the entire system and then deodorized it.  Halfway through the process, they took my $100+ air filter outside the clean it.  I was both angry and amazed at the size of the dust balls on my filter.  The air ducts were beyond filthy, and simply having the best air filter did nothing for the coating inside the air ducts.  Now you would think after all this education on my part and work on their part, we would be through.  No.
I recently did some remodeling and figured I’d get the air ducts cleaned in our 12 year old home. After obtaining 4 estimates between $572 and a whopping $3,075 for 25 vents and 2 air handlers, I knew I was in for a ride. I read through this blog and decided to use a $79 inspection camera I just found online (Home Depot) to take a look at all my ducts by removing the ceiling grilles first and then try to get into the ducts from the other end. From what I have just learned here, I believe that will take care of my “concerns”.
Is duct cleaning worth it? There is not a yes or no answer that suits everyone. On an Air Force base, the system was not air tight and there was leakage around the filters. The system got dirty. A professional company was called out. The Duct was big enough that a technician could go inside the metal duct and clean it. There was a new Air Handler installed and things were sealed up better. in this case it was worth it.
You may consider having your air ducts cleaned simply because it seems logical that air ducts will get dirty over time and should be occasionally cleaned. Provided that the cleaning is done properly, no evidence suggests that such cleaning would be detrimental. EPA does not recommend that the air ducts be cleaned routinely, but only as needed. EPA does, however, recommend that if you have a fuel burning furnace, stove or fireplace, they be inspected for proper functioning and serviced before each heating season to protect against carbon monoxide poisoning.
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